Modified interferon-beta (IFN-beta) polypeptides
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United States of America Patent
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Issued Date -
Jan 3, 2008
app pub date -
Mar 27, 2007
filing date -
Mar 28, 2006
priority date (Note) -
Abandoned
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Abstract
Provided are modified interferon-beta polypeptides and nucleic acid molecules encoding modified interferon-beta polypeptides and formulations containing the polypeptides and/or nucleic acid molecules. The modified polypeptides exhibit increased protein stability, including increased resistance to proteases. Also provided are methods of treatment by administering modified interferon-beta polypeptides.
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