Indole Derivatives Useful for Treating Resistance to Antitumor Agents
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United States of America Patent
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Issued Date -
Dec 27, 2007
app pub date -
Apr 27, 2005
filing date -
Apr 30, 2004
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Abandoned
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Abstract
The use of a group of indole compounds of formula (I) is described for treating tumours which have developed resistance to antitumour drugs. The compounds of formula (I) can be used in monotherapy, to treat tumours affected by drug resistance, or in co-therapy, as synergistic enhancers of the action of the aforesaid antitumour drugs. In addition, pharmaceutical compositions are described which comprise the indole derivatives of formula (I) in association with antitumour drugs the activity of which is to be enhanced.
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