ANTIHYPERTENSIVE THERAPY METHOD

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United States of America Patent

APP PUB NO 20070293552A1
SERIAL NO

11761499

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Methods and therapeutic combinations are provided for lowering blood pressure in a subject exhibiting resistance to a baseline antihypertensive therapy with one or more drugs, or a subject having diabetes and/or chronic kidney disease. A method of the invention comprises administering, in some embodiments adjunctively with a modified baseline therapy, a compound of formula (I) as defined herein. A therapeutic combination of the invention comprises a compound of formula (I); at least one diuretic; and at least one antihypertensive drug selected from ACE inhibitors, angiotensin II receptor blockers, beta-adrenergic receptor blockers and calcium channel blockers; wherein the at least one diuretic and/or the at least one antihypertensive drug are present at substantially less than a full dose.

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Patent Owner(s)

Patent OwnerAddress
GILEAD COLORADO INC7575 W 103RD AVENUE SUITE 102 WESTMINSTER CO 80021-5426

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Gorczynski, Richard J Westminster, CO 13 167

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