Antimicrobial polymer conjugates
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United States of America Patent
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Issued Date -
Dec 20, 2007
app pub date -
Mar 27, 2007
filing date -
Mar 27, 2006
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Abstract
The present invention relates to the conjugation of antimicrobial agents to water-soluble polymers to improve their clinical properties in terms of their pharmacokinetics, pharmacodynamics, and reduced immunogenicity. More specifically, the present invention relates to the conjugation of antimicrobial agents such as lysostaphin to poly(alkylene oxides), such as poly(ethylene glycol) (PEG).
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