OPTICAL APPARATUS FOR SIMULTANEOUSLY MEASURING THE SCATTERING AND CONCENTRATION OF SIGNALS OF MACROMOLECULES IN A FLOW CELL
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United States of America Patent
Stats
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N/A
Issued Date -
Dec 20, 2007
app pub date -
Apr 13, 2007
filing date -
Apr 13, 2006
priority date (Note) -
Abandoned
status (Latency Note)
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Non-US Coverage
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Abstract
This invention relates to a fiber optic apparatus for simultaneously measuring the scattering and concentration signals of macromolecules in a flow cell 3. The apparatus is based on the delivery/focusing of both a laser and ultraviolet light source to the same physical position in a low volume flow cell 4, via a bifurcated optical fiber 3. This configuration allows the light scattering and concentration signal changes associated with a macromolecular solution passing through the flow channel to be measured simultaneously. This invention also relates to a method that uses the optical apparatus 10 to determine properties of a macromolecular solution such as the ideal crystallization and/or formulation conditions (via B.sub.22) for a given protein solution.
First Claim
Other Claims data not available
Family
| Country | kind | publication No. | Filing Date |
|---|---|---|---|
| WO | A2 | WO2007121363 | Apr 13, 2007 |
International Classification(s)
- 2007 Application Filing Year
- G01J Class
- 1174 Applications Filed
- 611 Patents Issued To-Date
- 52.05 % Issued To-Date
Cited Art Landscape
Patent Citation Ranking
- 6 Citation Count
- G01J Class
- 3.21 % this patent is cited more than
- 18 Age