Sustained release oxycodone composition with acrylic polymer and metal hydroxide
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United States of America Patent
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Issued Date -
Dec 6, 2007
app pub date -
Jun 6, 2006
filing date -
Jun 6, 2006
priority date (Note) -
Abandoned
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Abstract
The invention is a controlled release composition comprising a therapeutic amount of an active ingredient in a controlled release matrix. The matrix comprises a combination of a pharmaceutically acceptable acrylic polymer and a metal hydroxide. The amount of metal hydroxide, relative to a given amount of acrylic polymer, is selected for and corresponds to a pre-determined release rate for said active ingredient. The compound is preferably used to provide controlled release dosage of oxycodone through a matrix of ammonio methacrylic polymer and magnesium hydroxide.
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