Plasminogen Activator Inhibitor-1 Inhibitor
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United States of America Patent
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Issued Date -
Nov 29, 2007
app pub date -
Sep 3, 2004
filing date -
Sep 11, 2003
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Abandoned
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Abstract
A medicament having inhibitory activity against plasminogen activator inhibitor-1, which comprises as an active ingredient a compound represented by the following general formula (I) or a salt thereof: wherein R.sup.1 and R.sup.2 represents an aromatic group which may be substituted, W represents a group selected from the following connecting group W-1: (wherein a bond at the left end binds to the carbon atom and a bond at the right end binds to the nitrogen atom, X represents sulfur atom or NH, Y represents oxygen atom or sulfur atom, R.sup.3 represents a hydrocarbon group, hydroxy group, or carboxy group), Z represents a single bond or a connecting group wherein a number of atoms in a main chain is 1 to 3.
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