CATIONIC PEPTIDES FOR siRNA INTRACELLULAR DELIVERY
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United States of America Patent
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Issued Date -
Nov 29, 2007
app pub date -
Feb 16, 2007
filing date -
May 25, 2006
priority date (Note) -
Abandoned
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Abstract
What is described is a composition for delivery of a RNA molecule to a cell, comprising: a double stranded RNA (dsRNA) molecule of about 15 to about 40 base pairs; and a polynucleotide delivery-enhancing peptide, comprising a region of alternating lysine and histidine residues, or of alternating D and L forms of arginine.
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