Bioreactor for organ reconstruction and augmentation
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United States of America Patent
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Issued Date -
Nov 29, 2007
app pub date -
Feb 12, 2007
filing date -
Feb 10, 2006
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Abandoned
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Abstract
Bioreactors are used in neo-organ production to allow for an appropriate environment for the maintenance of healthy culturing conditions from pre-wetting to shipment of the neo-organ. The closed system 'all-in-one bioreactor' is designed to allow for minimal exposure of the scaffold to the open air in order to maintain sterility. The design allows for the same container to be utilized for sterilization, pre-wetting, cell seeding, medium exchange, and shipment. The 'all-in-one' bioreactor also remains completely closed after the urothelial cell seeding step to the implantation at the clinical site. This allows for sufficient time for release testing to occur so the neo-organ can be implanted into the patient.
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