Compositions of less immunogenic and long-circulating protein-lipid complexes
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United States of America Patent
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Jan 25, 2011
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app pub date -
Mar 30, 2007
filing date -
Mar 30, 2006
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Abstract
Provided are lipidic particles comprising phosphatidylcholine, phosphatidylinositol and cholesterol. Also provided are compositions comprising the lipidic particles and having associated therewith therapeutic agents such as peptides, polypeptides or proteins. In these compositions, the therapeutic agents have reduced immunogenicity and/or longer circulating time. These compositions can be used for therapeutic administration of the peptides, polypeptides and/or proteins.
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