Mutant G Genes of the Trout Viral Haemorrhagic Septicaemia Virus (Vhsv) and Applications Thereof
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Aug 11, 2005
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Aug 27, 2004
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Abstract
The invention relates to mutant G genes of viral haemorrhagic septicaemia virus (VHSV) in rainbow trout, which encode mutant G proteins of VHSV with defective or null binding to cells that can be infected by VHSV. Said mutant G genes of VHSV can be used, among other applications, to produce vaccines (DNA vaccines or attenuated live vaccines) for preventing disease caused by VHSV in animals that can be infected by VHSV, generating non-human transgenic animals, and developing reagents for the diagnosis of infection caused by VHSV.
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