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Abstract

The invention relates to a method for producing 2-amino-4,6-dichloro-5-formamidopyrimidine from 2,5-diamino-4,6-dihydroxypyrimidine or a salt thereof. According to said method, a) 2,5-diamino-4,6-dihydroxypyrimidine or the salt or tautomer forms thereof are reacted with a chlorination agent and a formamide of formula (I) wherein R.sup.1 and R.sup.2 independently represent a C.sub.1-C.sub.4 alkyl radical or --R.sup.1-R.sup.2-- represents --(CH2).sub.n-- where n=4-6, or --(CH.sub.2).sub.2-0-(CH.sub.2).sub.2--, without adding a solvent, at a temperature of between 50 and 130.degree. C., b) the reaction product obtained in step a) is reacted with water at a temperature of between 0 and 100.degree. C., and regulated to a pH value of between 1 and 6 with an inorganic base, and c) the aqueous reaction mixture obtained in step b) is left to react at a temperature of between 70 and 120.degree. C. under hydrolysis to form 2-amino-4,6-dichloor-5-formamidopyrimidine. The inventive method enables satisfactory yields and high levels of purity of the end product to be obtained. As a result of the significantly reduced reaction volumes due to the solvent, auxiliary substances and residual substances saved, and the significantly simplified method, the costs incurred in the production of 2-amino-4,6-dichloro-5-formylaminopyrimidine are significantly reduced.

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