PROVISION OF VASCULAR GRAFTS WITH AN ACTIVE PRINCIPLE
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United States of America Patent
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Issued Date -
Nov 15, 2007
app pub date -
Apr 4, 2007
filing date -
Apr 6, 2006
priority date (Note) -
Abandoned
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Abstract
One or more substances of the group consisting of gentamicin palmitate, gentamicin myristate, gentamicin laurate, tobramycin palmitate, tobramycin myristate, tobramycin laurate, amikacin palmitate, amikacin myristate, amikacin laurate, vancomycin palmitate, vancomycin laurate, and vancomycin myristate are suitable for providing vascular grafts with an antithrombogenically active principle. The appropriate method for providing vascular grafts with an antithrombogenically active principle particularly comprises the following steps of A immersing the graft body in an alcoholic solution or an alcoholic solution with a readily volatile solvent, such as chloroform, wherein the alcoholic solution is of a member of the group consisting of gentamicin palmitate, gentamicin myristate, gentamicin laurate, tobramycin palmitate, tobramycin myristate, tobramycin laurate, amikacin palmitate, amikacin myristate, amikacin laurate, vancomycin palmitate, and vancomycin myristate, or of spraying said solution on said graft body, and of B vaporizing said alcoholic solvent.
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