Preparation for preventing or treating disorders caused by toxic constituents contained in fiber combustion smoke
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United States of America Patent
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Issued Date -
Nov 15, 2007
app pub date -
May 23, 2006
filing date -
May 12, 2006
priority date (Note) -
Abandoned
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Abstract
Preventive or therapeutic agents for controlling various disorders induced by toxic substances in smoke produced by the combustion of fibers such as tobacco are disclosed. A polypeptide of the thioredoxin family (TRX) prevents toxic substances in smoke, produced by the combustion of fibers such as tobacco, from inducing inflammatory reactions and tissue fibrosis. Accordingly, TRX is effective for controlling of a wide range of disorders caused by toxic substances contained in smoke produced by combustion of fibers. The object of the present invention is to provide the preventive or therapeutic agents for disorders caused by toxic substances contained in smoke produced by combustion of fibers comprising an effective amount of polypeptide of thioredoxin family and/or one or more of its inducers.
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