Covalent Grafting of Hydrophobic Substances on Collagen

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United States of America Patent

APP PUB NO 20070260299A1
SERIAL NO

11664637

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A hydrophobic grafted collagen, a method for preparing same and use thereof, in particular in therapy, are provided. Hydrophobic substances or molecules are grafted by covalent bonds on reactive amino acid residues of collagen molecules. The chemical linkages serve to modify the physico-chemical and biological properties of collagen and/or its derivatives. In particular, the introduction of hydrophobic residues enable the hydrophilic character of collagen to be modulated and its chemotactic properties involved in cell adhesion and growth to be modified.

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Patent Owner(s)

Patent OwnerAddress
INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE LYON20 AVENUE ALBERT EINSTEIN VILLEURBANNE CEDEX 69621

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Gagnieu, Christian Chassieu, FR 16 182

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  • 7 Citation Count
  • A61K Class
  • 8.93 % this patent is cited more than
  • 18 Age
Citation count rangeNumber of patents cited in rangeNumber of patents cited in various citation count ranges30718326412821326750302016134901 - 1011 - 2021 - 3031 - 4041 - 5051 - 6061 - 7071 - 8081 - 9091 - 100100 +010020030040050060070080090010001100120013001400150016001700180019002000

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