Nucleotide mimics and their prodrugs
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United States of America Patent
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Oct 6, 2009
Grant Date -
Nov 8, 2007
app pub date -
Jun 14, 2007
filing date -
Feb 28, 2002
priority date (Note) -
Expired
status (Latency Note)
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Abstract
The present invention relates to nucleoside diphosphate mimics and nucleoside triphosphate mimics, which contain diphosphate or triphosphate moiety mimics and optionally sugar-modifications and/or base-modifications. The nucleotide mimics of the present invention, in a form of a pharmaceutically acceptable salt, a pharmaceutically acceptable prodrug, or a pharmaceutical formulation, are useful as antiviral, antimicrobial, and anticancer agents. The present invention provides a method for the treatment of viral infections, microbial infections, and proliferative disorders. The present invention also relates to pharmaceutical compositions comprising the compounds of the present invention optionally in combination with other pharmaceutically active agents.
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