Drug Delivery from Embolic Agents
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United States of America Patent
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N/A
Issued Date -
Nov 8, 2007
app pub date -
Aug 3, 2004
filing date -
Aug 3, 2004
priority date (Note) -
Abandoned
status (Latency Note)
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Abstract
A pharmaceutical composition for embolisation of blood vessels, especially for benign tumours, comprises a polymeric embolic agent and, associated with the polymer in a releasable form, a local anaesthetic agent. The polymer is preferably in particulate form, such as in the form of microspheres. A suitable polymer is a crosslinked polyvinyl alcohol polymer formed by the copolymerisation of PVA macromer with other ethylenically unsaturated monomers. The composition provides a synergistic treatment for the symptoms of tumours such as uterine fibroids, leading to size regression as well as pain relief.
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