Substituted 1-Benzyl-4-Substituted Piperazine Analogues
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United States of America Patent
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app pub date -
Jun 15, 2007
filing date -
Apr 7, 2004
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Abstract
Compounds of Formula I are provided, in which variables are as described herein: Such compounds may be used to modulate MCH binding to MCH receptors in vivo or in vitro, and are particularly useful in the treatment of a variety of metabolic, feeding and sexual disorders in humans, domesticated companion animals and livestock animals. Pharmaceutical compositions and methods for treating such disorders are provided, as are methods for using such ligands for detecting MCH receptors (e.g., receptor localization studies).
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