Methods for the development of a biomolecule assay

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United States of America Patent

APP PUB NO 20070231909A1
SERIAL NO

11580221

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Abstract

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The present teachings provide methods for the development of a mass spectrometric based assay for a protein in a sample using parent-daughter ion transition monitoring (PDITM). In various aspects, the present teachings provide methods for developing a mass spectrometric based assay for a protein in a sample without the use of a standard for the protein. In various embodiments, the sample comprises proteolytic fragments of a protein which is present in low abundance in the physiological fluid from which it is derived.

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Patent Owner(s)

Patent OwnerAddress
APPLIED BIOSYSTEMS LLC5823 NEWTON DRIVE CARLSBAD CA 92008

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Hunter, Christie L San Mateo, CA 13 270

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