Nucleic acid assembly optimization using clamped mismatch binding proteins
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United States of America Patent
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Issued Date -
Oct 4, 2007
app pub date -
Mar 31, 2006
filing date -
Mar 31, 2006
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Abandoned
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Abstract
Certain aspects of the present invention provide methods for increasing the fidelity of multiplex nucleic acid assembly reactions using one or more mismatch binding proteins. Aspects of the invention also provide kits, compositions, devices, and systems for enriching nucleic acid samples for nucleic acids containing correct sequences using clamped forms of one or more mismatch binding proteins.
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