Transdermal Steriod for Formulation
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United States of America Patent
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Issued Date -
Oct 4, 2007
app pub date -
Apr 28, 2004
filing date -
Apr 28, 2004
priority date (Note) -
Abandoned
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Abstract
Compounds of formula (I) (in which R.sup.1; R.sup.2, R.sup.3 and R.sup.4 are the same as or different from each other and each represents an oxo group, a hydroxy group, a mercapto group, a hydrogen atom, a halogen atom, an alkoxy group or an aryloxy group; and the dotted line indicates that there may be a single or double bond between one of the respective pairs of carbon atoms) and esters thereof can be administered by transdermal administration. They are particularly effective when applied as a patch, preferably with an adhesive comprising a copolymer of from 40 to 60% by weight of methoxyethyl acrylate, from 30 to 40% by weight of lauryl acrylate or lauryl methacrylate and from 10 to 25% by weight of a polar monomer.
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