Expression Cassette

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United States of America Patent

APP PUB NO 20070224675A1
SERIAL NO

11578452

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Abstract

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An expression cassette comprises targeting sites flanking a Cre fusion gene and a Cre coding sequence interrupted by an intron. This cassette can be used for the generation CreAoxP constructs and to reduce toxicity caused by the over-expression of Cre in target cells.

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Patent Owner(s)

Patent OwnerAddress
ARK THERAPEUTICS LTD1 FITZROY MEWS LONDON W1T 6DE

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Airenne, Kari Juhani Kuopio, FI 9 4
Mahonen, Anssi Kuopio, FI 4 1
Yla-Herttuala, Seppo Kuopio, FI 55 396

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