Novel Vaccine Containing Adjuvant Capable Of Inducing Mucosal Immunity

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United States of America Patent

APP PUB NO 20070219149A1
SERIAL NO

10567766

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention provides an adjuvant that possesses a greater adjuvant potential than that of a conventional adjuvant, and that is capable of producing a protective reaction across different strains. This problem has been solved by the finding that a double-stranded RNA (for example, Poly(I:C)) unexpectedly exhibits the above capability when used in combination with a subunit antigen. Accordingly, the present invention provides a vaccine for mucosal administration containing A) a double-stranded RNA and B) a subunit antigen or inactivated antigen of a pathogen.

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Patent Owner(s)

Patent OwnerAddress
TORAY INDUSTRIES INC1-1 NIHONBASHI-MUROMACHI 2-CHOME CHUO-KU TOKYO 103-8666
THE RESEARCH FOUNDATION FOR MICROBIAL DISEASES OF OSAKA UNIVERSITYSUITA-SHI OSAKA 565-0871
JAPAN AS REPRESENTED BY THE DIRECTOR-GENERAL OF NATIONAL INSTITUTE OF INFECTIOUS DISEASESSHINJUKU-KU TOKYO 162-8640

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Hasegawa, Hideki Bunkyo-ku, JP 86 670
Kurata, Takeshi Kokubunji-shi, JP 35 225
Moriyama, Masami Yokohama-shi, JP 3 23
Sata, Tetsutarou Koto-ku, JP 2 23
Tamura, Shin-ichi Suita-shi, JP 1 22
Tanimoto, Takeshi Suita-shi, JP 13 112

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