Convergent Synthesis for Kahalalide Compounds
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United States of America Patent
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Issued Date -
Sep 6, 2007
app pub date -
Apr 22, 2005
filing date -
Apr 22, 2004
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Abandoned
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Abstract
New synthetic routes to kahalalide compounds are provided. These are based on convergent approaches using orthogonal protecting schemes, where a better control of the intermediates is taken. Kahalalide F or a mimic of kahalalide F is synthesised by coupling a cyclic part with a side chain fragment, e.g. according to the reaction (1)
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