METHOD AND APPARATUS FOR MAGNETIC MIXING IN MICRON SIZE DROPLETS
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United States of America Patent
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Issued Date -
Sep 6, 2007
app pub date -
Mar 2, 2007
filing date -
Mar 3, 2006
priority date (Note) -
Abandoned
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Abstract
Active mixing by magnetic stirring is demonstrated inside a picoliter-size liquid droplet. Magnetic microspheres are added to the droplet, which form aligned chains under the influence of a homogeneous magnetic field. When the magnetic field is rotated, the chains also rotate synchronously. Viscous interaction between the particle-chains and the liquid induces advective motion inside the droplet thereby enhancing mixing which is otherwise diffusion-limited. The concept can be effectively used to create a lab-in-a-droplet for MEMS (Micro-Electrical-Mechanical Systems) and Bio-MEMS applications.
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