COMPOUNDS AND METHODS FOR MODULATING ADHESION MOLECULE FUNCTION

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United States of America Patent

SERIAL NO

11616733

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Abstract

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Modulating agents and methods for enhancing or inhibiting cadherin-mediated functions are provided. The modulating agents comprise at least an HAV binding motif, an analogue or peptidomimetic thereof, or an antibody or fragment thereof that specifically binds to such a motif. Modulating agents may additionally comprise one or more cell adhesion recognition sequences recognized by cadherins and/or other adhesion molecules. Such modulating agents may, but need not, be linked to a targeting agent, drug and/or support material.

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Patent Owner(s)

Patent OwnerAddress
ADHEREX TECHNOLOGIES INCOTTAWA ONTARIO K1G 5Z3

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Blaschuk, Orest W Westmount, QC 68 735
Doherty, Patrick Twickenham, GB 17 98
Gour, Barbara J Kemptville, ON 63 694

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