CD8 AS AN INHIBITOR OF THE CELLULAR IMMUNE SYSTEM
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United States of America Patent
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app pub date -
Apr 4, 2007
filing date -
Oct 28, 1997
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Abstract
This invention is directed to a method for inhibiting cytotoxic T lymphocyte (CTL) activity in which soluble CD8 is used as the inhibitor. The invention is further directed to soluble forms of the CD8 molecule which can be administered to a patient. The method of this invention is particularly useful for immunosuppressive therapy in which inhibition of CTL activity is desirable, for example, in patients undergoing transplantation.
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