Transgenic mouse capable of over-expressing VE-PTP
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United States of America Patent
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Issued Date -
Aug 9, 2007
app pub date -
Nov 10, 2005
filing date -
Nov 15, 2004
priority date (Note) -
Abandoned
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Abstract
The present invention relates generally to a transgenic mouse. In particular, the present invention relates to a transgenic mouse whose genome comprises a TetO-VE-PTP transgene. The present invention also relates to a double transgenic mouse whose genome comprises the transgenes TetO-VE-PTP and Tie2-tTA, which is capable of conditionally over-expressing VE-PTP which is contingent on the presence of doxycycline. The present invention also relates to methods of generating a transgenic mouse whose genome comprises a TetO-VE-PTP and a double transgenic mouse whose genome comprises the transgenes TetO-VE-PTP and Tie2-tTA.
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