COMPOSITIONS AND METHODS FOR REGULATING COMPLEMENT SYSTEM
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United States of America Patent
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Issued Date -
Aug 2, 2007
app pub date -
Dec 22, 2006
filing date -
Dec 22, 2005
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Abstract
The disclosure provided herein provides for methods and compositions for modulating the human complement pathway by reducing the expression or production of one or more complement pathway protein and uses for such methods for treating diseases including ocular disease and macular degeneration related disease. The invention also includes active agents for mediating the modulation of the complement pathway including siRNA designed to cause the RNAi-mediated degradation of complement pathway proteins.
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