Methods and compounds for disruption of CD40R/CD40L signaling in the treatment of Alzheimer's disease
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United States of America Patent
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Issued Date -
Jul 12, 2007
app pub date -
Sep 18, 2006
filing date -
Jun 1, 1999
priority date (Note) -
Abandoned
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Abstract
The subject invention provides methods of treating amyloidogenic diseases, comprising the administration of therapeutically effective amounts of a composition comprising a carrier and an agent that interferes with the interaction of CD40L and CD40R to an individual afflicted with an amyloidogenic disease. Also provided are methods and/or assay systems for the identification of compounds or other small molecules capable of disrupting the CD40R/CD40L signaling pathway.
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