NEUTRALIZING ANTIBODIES AGAINST PRIMATE PSGL-1 AND USES THEREFOR
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United States of America Patent
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Issued Date -
Jul 12, 2007
app pub date -
Dec 8, 2006
filing date -
Dec 9, 2005
priority date (Note) -
Abandoned
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Abstract
This application relates to neutralizing antibodies that specifically bind primate PSGL-1, as well as their production and use. The antibodies reduce one or more activities of PSGL-1, such as human PSGL-1. Methods to detect or quantitate PSGL-1 in a biological sample by adding an antibody that specifically binds to PSGL-1 to the sample are provided. Further, methods to treat a primate PSGL-1 associated disorder, such as a human disorder, by administering a PSGL-1 specific antibody are also provided.
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