Novel translocation assay
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United States of America Patent
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Issued Date -
Jun 21, 2007
app pub date -
Aug 9, 2004
filing date -
Aug 8, 2003
priority date (Note) -
Abandoned
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Abstract
The present invention relates to a novel in vitro assay for determining the level of a protein, in particular, a membrane transport protein that is located at the plasma membrane of a cell compared to the level of the protein in the cell. The process of the invention is also useful for determining the level of recycling of a membrane transport protein. The present invention additionally provides a process for identifying an agent that modulates the translocation of a protein, in particular, a membrane transport protein, to the plasma membrane and, as a consequence, the activity of that protein.
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