Chemically modified oligonucleotides for use in modulating micro RNA and uses thereof

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United States of America Patent

APP PUB NO 20070123482A1
SERIAL NO

11502158

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Abstract

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This invention relates generally to chemically modified oligonuceotides useful for modulating expression of microRNAs and pre-microRNAs. More particularly, the invention relates to single stranded chemically modified oligonuceotides for inhibiting microRNA and pre-microRNA expression and to methods of making and using the modified oligonucleotides.

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Patent Owner(s)

Patent OwnerAddress
REGULUS THERAPEUTICS INC1896 RUTHERFORD ROAD CARLSBAD CA 92008

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Manoharan, Muthiah Weston, MA 491 18658
Rajeev, Kallanthottathil G Cambridge, MA 260 8660
Stoffel, Markus New York, NY 25 544

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