Treatment with immunoregulatory t cells
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United States of America Patent
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app pub date -
Nov 5, 2004
filing date -
Nov 5, 2003
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Abstract
Methods and compositions are provided for the treatment of an autoimmune disease. The methods include administering immunoregulatory T cells (T.sub.regs) to patients. The therapeutic T.sub.regs can express the CD25, CD4, and/or ICOS antigens. The therapeutic T cells can be CD25.sup.+ ICOS.sup.+, CD4.sup.+ICOS.sup.+, and/or CD25.sup.+ CD4.sup.+ ICOS.sup.+, and they can be provided by a donor.
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