Treatment with immunoregulatory t cells

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United States of America Patent

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10578797

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Abstract

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Methods and compositions are provided for the treatment of an autoimmune disease. The methods include administering immunoregulatory T cells (T.sub.regs) to patients. The therapeutic T.sub.regs can express the CD25, CD4, and/or ICOS antigens. The therapeutic T cells can be CD25.sup.+ ICOS.sup.+, CD4.sup.+ICOS.sup.+, and/or CD25.sup.+ CD4.sup.+ ICOS.sup.+, and they can be provided by a donor.

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Patent Owner(s)

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NEW ENGLAND MEDICAL CENTER HOPITALS INCNEMCH BOX 817 750 WASHINGTON STREET BOSTON MA 02111

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Foss, Francine M Woodbridge, CT 3 21
Xie, Yong Belmont, MA 136 763

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