Combination therapy for the treatment of immunoinflammatory disorders

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United States of America Patent

APP PUB NO 20070110685A1
SERIAL NO

11454202

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The invention features a method for treating a patient diagnosed with, or at risk of developing, an immunoinflammatory disorder by administering a non-steroidal immunophilin-dependent immunosuppressant (NsIDI) and a Group A enhancer (e.g., antifungal agent, antigout agent, anti-infective agent, antiprotozoal agent, antiviral agent, humectant, sunscreen, vitamin D compound, microtubuline inhibitor, or zinc salt) or analog or metabolite thereof to the patient. The invention also features a pharmaceutical composition containing an NsIDI and Group A enhancer or analog or metabolite thereof for the treatment or prevention of an immunoinflammatory disorder.

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Patent Owner(s)

Patent OwnerAddress
ZALICUS INC245 FIRST STREET THIRD FLOOR CAMBRIDGE MA 02142

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Auspitz, Benjamin A Cambridge, MA 20 1001
Brasher, Bradley B Natick, MA 7 195
Chappell, Todd W Boston, MA 19 349
Frank, Michael G Boston, MA 8 311
Grau, Daniel Arlington, MA 6 162
Jost-Price, Edward Roydon West Roxbury, MA 33 1095
Lederman, Seth New York, NY 70 716
Manivasakam, Palaniyandi West Roxbury, MA 30 383
Orlow, Seth New York, NY 2 67
Sachs, Noah South Boston, MA 6 134
Smith, Brendan Somerville, MA 31 443

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