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Abstract

An apparatus and method for dispensing low volumes of an analyte solution. The apparatus comprises: (a) a receiver defining an ejection cavity and an outlet downstream of and in fluid communication with the ejection cavity; (b) first and second fluid conduits coupled to the receiver and defining respective first and second fluid flow paths in fluid communication with the ejection cavity; (c) an analyte generating apparatus operatively coupled to the first fluid conduit and operable to deliver analyte solution along the first fluid flow path to the ejection cavity; and (d) a dispensing mechanism operatively coupled to the second fluid conduit and operable to deliver a fluid buffer along the second fluid flow path into the ejection cavity to displace analyte solution present therein through the outlet. The method involves filling the ejection cavity with an analyte solution at a selected rate and injecting a fluid buffer into the injection cavity to displace the analyte solution through the outlet.

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