Sirt1 and genetic disorders

Number of patents in Portfolio can not be more than 2000

United States of America Patent

APP PUB NO 20070105109A1
SERIAL NO

10562389

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Alzheimer's Disease (AD) is genetically linked to a locus that includes the SIRT1 gene. This disclosure includes methods and compositions for evaluating genetic variances, e.g., within this locus, and for the association of these variances with AD. The disclosure also includes methods and compositions for modulating SIRT1 expression and/or activity. These methods and compositions can be used in the prevention or treatment of AD.

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Patent Owner(s)

Patent OwnerAddress
ELIXIR PHARMACEUTICALS INCONE KENDALL SQUARE BUILDING 1000-FIFTH FLOOR CAMBRIDGE MA 02139

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Brass, Laura Cambridge, MA 7 55
Geesaman, Bard J Cambridge, MA 8 185

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