Use of simple amino acids to form porous particles
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United States of America Patent
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app pub date -
Dec 12, 2006
filing date -
Aug 25, 1999
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Abandoned
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Abstract
Particles having a tap density of less than 0.4 g/cm.sup.3 include a hydrophobic amino acid or salt thereof and a therapeutic, prophylactic or diagnostic agent or any combination thereof. Preferred particles include a phospholipid, have a median geometric diameter between about 5 and about 30 microns and an aerodynamic diameter between about 1 and about 5 microns. The particles can be formed by spray-drying and are useful for delivery to the pulmonary system.
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