Compositions and methods for determining susceptibility of hepatitis C virus to anti-viral drugs
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Jun 14, 2006
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Jul 30, 1997
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Abstract
The present invention provides methods for determining the susceptibility of a pathogenci flavirus to anti-viral compounds. This invention also provides methods for determining anti-viral drug susceptibility in a patient infected with a flavivirus. This invention also provides a method for evaluating the biological effectiveness of a candidate anti-viral drug compound. The methods are useful for identifying effective drug regimens for the treatment of flaviviral infections, and identifying and assessing the biological effectiveness of potentia therapeutic compounds. Compositions including resistance test vectors and host cells transformed with resistance test vectors are provided.
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