Compounds and methods for modulating phosphodiesterase 10A
Number of patents in Portfolio can not be more than 2000
United States of America Patent
Stats
-
N/A
Issued Date -
N/A
app pub date -
Aug 23, 2006
filing date -
Oct 7, 1999
priority date (Note) -
Abandoned
status (Latency Note)
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Abstract
Novel compounds that modulate PDE10A, a gene that is primarily expressed in medium spiny neurons of the mammalian striatum and has been found to inhibit striatal output by reducing spiny medium excitability and effect cAMP and cGMP signalling cascades in vivo in rats, and methods for treating psychosis and schizophrenia using the novel compounds. Methods for screening for further compounds to modulate PDE10A activity are also taught.
First Claim
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Family

- 15 United States
- 10 France
- 8 Japan
- 7 China
- 5 Korea
- 2 Other
Patent Owner(s)
Patent Owner | Address | |
---|---|---|
DALHOUSIE UNIVERSITY | 1344 SUMMER STREET SUITE 207 HALIFAX NOVA SCOTIA B3H 4R2 |
International Classification(s)

- 2006 Application Filing Year
- A61K Class
- 9598 Applications Filed
- 4848 Patents Issued To-Date
- 50.52 % Issued To-Date
Inventor(s)
Inventor Name | Address | # of filed Patents | Total Citations |
---|---|---|---|
Denovan-Wright, Eileen M | Halifax, CA | 2 | 21 |
# of filed Patents : 2 Total Citations : 21 | |||
Robertson, Harold A | Halifax, CA | 2 | 21 |
# of filed Patents : 2 Total Citations : 21 | |||
Weaver, Donald | Halifax, CA | 19 | 251 |
# of filed Patents : 19 Total Citations : 251 |
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Patent Citation Ranking
- 19 Citation Count
- A61K Class
- 62.20 % this patent is cited more than
- 18 Age
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Maintenance Fees
Fee | Large entity fee | small entity fee | micro entity fee | due date |
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Fee | Large entity fee | small entity fee | micro entity fee |
---|---|---|---|
Surcharge after expiration - Late payment is unavoidable | $700.00 | $350.00 | $175.00 |
Surcharge after expiration - Late payment is unintentional | $1,640.00 | $820.00 | $410.00 |
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