Compounds and methods for modulating phosphodiesterase 10A

Number of patents in Portfolio can not be more than 2000

United States of America Patent

SERIAL NO

11508755

Stats

ATTORNEY / AGENT: (SPONSORED)

Importance

Loading Importance Indicators... loading....

Abstract

See full text

Novel compounds that modulate PDE10A, a gene that is primarily expressed in medium spiny neurons of the mammalian striatum and has been found to inhibit striatal output by reducing spiny medium excitability and effect cAMP and cGMP signalling cascades in vivo in rats, and methods for treating psychosis and schizophrenia using the novel compounds. Methods for screening for further compounds to modulate PDE10A activity are also taught.

First Claim

See full text

Other Claims data not available

Family

Loading Family data... loading....

Patent Owner(s)

Patent OwnerAddress
DALHOUSIE UNIVERSITY1344 SUMMER STREET SUITE 207 HALIFAX NOVA SCOTIA B3H 4R2

International Classification(s)

loading....
  • 2006 Application Filing Year
  • A61K Class
  • 9598 Applications Filed
  • 4848 Patents Issued To-Date
  • 50.52 % Issued To-Date
Click to zoom InYear of Issuance% of Matters IssuedCumulative IssuancesYearly Issuances2006200720082009201020112012201320142015201620172018201920202021202220230255075100

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Denovan-Wright, Eileen M Halifax, CA 2 21
Robertson, Harold A Halifax, CA 2 21
Weaver, Donald Halifax, CA 19 251

Cited Art Landscape

Load Citation

Patent Citation Ranking

  • 19 Citation Count
  • A61K Class
  • 62.20 % this patent is cited more than
  • 18 Age
Citation count rangeNumber of patents cited in rangeNumber of patents cited in various citation count ranges30718326412821326750302016134901 - 1011 - 2021 - 3031 - 4041 - 5051 - 6061 - 7071 - 8081 - 9091 - 100100 +010020030040050060070080090010001100120013001400150016001700180019002000

Forward Cite Landscape

Load Citation