Hybrid molecules QA where Q is an aminoquinoline and A is an antibiotic residue, the synthesis and uses thereof as antibacterial agents
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United States of America Patent
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Sep 7, 2006
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Jul 30, 2004
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Abstract
The invention concerns an aminoquinoline-antibiotic hybrid compound of general formula (I): Q--(Y.sub.1).sub.p--(U).sub.p--(Y.sub.2).sub.p-A: wherein Q represents an aminoquinoline, (Y.sub.1).sub.p(U).sub.p--(Y.sub.2).sub.p'' is an optional spacer and A is an antibiotic residue. The invention enables the antibiotic residue activity to be unexpectedly enhanced.
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