Methods for predicting drug sensitivity in patients afflicted with an inflammatory disease
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United States of America Patent
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app pub date -
Nov 3, 2006
filing date -
Sep 6, 2001
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Abstract
Methods are disclosed for predicting the efficacy of a drug for treating an inflammatory disease in a human patient, including: obtaining a sample of cells from the patient; obtaining a gene expression profile of the sample in the absence and presence of in vitro modulation of the cells with specific cytokines and/or mediators; and comparing the gene expression profile of the sample with a reference gene expression profile, wherein similarities between the sample expression profile and the reference expression profile predicts the efficacy of the drug for treating the inflammatory disease in the patient.
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