Importance

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Abstract

The present invention generally relates to chemical, biological, and/or biochemical reactor microreactors and other reaction systems such as microreactor systems, as well as systems and methods for constructing and using such devices. In one aspect, a reactor on a chip has a container in fluid communication with a channel, and the channel is in fluid communication with a port for connecting the container to a source of fluid to be introduced into the container. The container can be very small, for example, with a volume of less than about 2 milliliters, and the fluid channel can have a channel volume of less than 1.5 percent of the container volume. According to another aspect, the combined volume of the port volume and the channel volume can be less than about 10 percent of the container volume. Such a configuration may increase the percentage of added fluid that reaches the container. In fed-batch operations, species may be added and removed via the same channel so that a gas headspace can be maintained within the reactor.

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First Claim