Simultaneous quantification of nucleic acids in diseased cells
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United States of America Patent
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app pub date -
May 27, 2004
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Oct 18, 2000
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Abstract
A process for assessing mitochondrial toxicity of a compound that includes contacting nucleic acids from a host with an amplification reaction mixture that contains at least two primers that provide detectable signals, wherein: a first primer provides a first detectable signal upon amplification of a host mitochondrial nucleic acid; a second primer provides a second detectable signal upon amplification of a host nuclear nucleic acid; and comparing the first and second detectable signals.
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