COMPUTING METHODS FOR CONTROL OF HIGH-THROUGHPUT EXPERIMENTAL PROCESSING, DIGITAL ANALYSIS, AND RE-ARRAYING COMPARATIVE SAMPLES IN COMPUTER-DESIGNED ARRAYS

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United States of America Patent

SERIAL NO

11467096

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Abstract

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Computer-controlled automated high-throughput systems can be used to design, prepare, process, screen, and analyze a large number of samples in removable sample vials each containing a compound of interest formulated with differing component combinations and varying concentrations. The computer-controlled methods of the present invention allow for a determination of the effects of additional or inactive components, such as excipients, carriers, enhancers, adhesives, additives, and the like, on the compound of interest, such as a pharmaceutical. The invention thus encompasses the computer systems, computer methods, and computer-program products for computer-controlled automated high-throughput testing of experimental formulations in order to identify experimental formulations that can be further processed. Identified experimental formulations from multiple arrays can be removed and re-arrayed together to form a new array for further processing.

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Patent Owner(s)

Patent OwnerAddress
TRANSFORM PHARMACEUTICALS INC610 LINCOLN STREET WALTHAM MA 02451

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Almarsson, Orn Shrewsbury, MA 71 1536
Chen, Hongming Acton, MA 73 1423
Cima, Michael J Winchester, MA 151 10097
Gonzalez-Zugasti, Javier P N. Billerica, MA 7 126
Johnson, Alasdair Y Newburyport, MA 7 167
Lemmo, Anthony V Sudbury, MA 24 375
Levinson, Douglas A Sherborn, MA 50 2064
McNulty, Christopher Arlington, MA 20 307

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