Diagnostic imaging contrast agents with extended blood retention
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United States of America Patent
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Issued Date -
Jan 25, 2007
app pub date -
Sep 25, 2006
filing date -
Feb 1, 1995
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Abstract
The present invention relates to contrast agents for diagnostic imaging with prolonged blood retention. In particular, this invention relates to novel compounds that are characterized by an image enhancing moiety (IEM); a protein plasma binding moiety (PPBM); and a blood half-life extending moiety (BHEM). This invention also relates to pharmaceutical compositions comprising these compounds and to methods of using the compounds and compositions for blood half-life extension and contrast enhancement of diagnostic imaging.
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