Optimized Sample Injection Structures in Microfluidic Separations
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United States of America Patent
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Issued Date -
Jan 25, 2007
app pub date -
Mar 30, 2006
filing date -
Mar 30, 2005
priority date (Note) -
Abandoned
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Abstract
Methods and apparatus for providing improved sample injection systems and microfluidic devices with structures such as microchambers that can provide relatively large sample volumes. The microchambers can be formed with a geometry to define sample plugs that can be symmetrical from the perspective of a sample load channel and a sample waste channel. Upon selective application of electrical fields, a defined amount of sample can be injected or loaded from a sample channel into the relatively larger interior volume of a sample chamber prior to ejection into a separation channel so that a sample volume can be separated electrophoretically.
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