Mitotic index assay
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United States of America Patent
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Issued Date -
Jan 18, 2007
app pub date -
Jun 20, 2006
filing date -
Jun 21, 2005
priority date (Note) -
Abandoned
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Abstract
Mitosis of cells is determined, particularly in the presence of a candidate agent, using cells comprising members of an enzyme fragmentation complex pair, where one of the members is in the nucleus and the other member is in the cytoplasm. By growing the cells where mitosis may occur, one adds a substrate providing a detectable product, where the production of the detectable product is indicative of mitosis.
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