Mammalian IAP gene family, primers, probes, and detection methods
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United States of America Patent
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Issued Date -
Jan 11, 2007
app pub date -
Dec 22, 2005
filing date -
Aug 4, 1995
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Abstract
Disclosed is substantially pure DNA encoding mammalian IAP polypeptides; substantially pure polypeptides; and methods of using such DNA to express the IAP polypeptides in cells and animals to inhibit apoptosis. Also disclosed are conserved regions characteristic of the IAP family and primers and probes for the identification and isolation of additional IAP genes. In addition, methods for treating diseases and disorders involving apoptosis are provided.
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